Summary Education Experience Countries Visited 360° Lab View
Comprehensive and in-depth knowledge in vascular biology, Redox Biology ,cardiovascular and stem cell biology. Developed techniques to isolate beating cardiomyocytes from rat pups and mastered isolation of stem cells from Umblical Cord, Bone marrow and cardiac explants.
Developed a CAM model to study angiogenesis and has developed Hypoxia models to study various therapeutic targets.
Discovered the anti-apoptotic property of EETS, leading to the development of possible drugs for myocardial Ischemia.
Director and Head, Centre for Biotechnology, Alagappa College of Technology, Anna University, Chennai 600 025 | May-2016 to April 2019. |
Associate Professor, Centre for Biotechnology, Alagappa College of Technology, Anna University, Chennai | June-2012 to June 2015 |
Assistant Professor, Centre for Biotechnology, Alagappa College of Technology, Anna University, Chennai | December-2009 to May- 2012. |
Deputy Director, Centre for International Affairs, Anna University, Chennai | April-2013 to August-2013. |
• Tissue Engineering
• Angiogenesis
• Cell signalling
• Hypoxia
• Stem cell Technology
• Cardiovascular Therapy
• Cancer Biology
• To create a platform that fosters inter-disciplinary collaborations toward bench to bedside translation of stem cell technologies for heart and vascular disease management
• To study the role of Wnt signaling in Stem cell differentiation
• Role of conditioned media from MScs
• Effects of micro-environmental stress on the regenerative activity of mesenchymal stem cells.
My lab focuses on further understanding of stem cell behavior, characterization, manipulation, expansion and therapeutic delivery
• In vitro studies in enhancing CSCs survival, proliferation and subsequent differentiation to functional Cardiomyocytes under hypoxic conditions.
• Analysis of anti-apoptotic and cyto protective pathways give clue regarding molecular mechanisms involved in decreasing the extent of cell death.
• Isolation, culture and characterization of CSCs from rat heart biopsies by explant method
• Understanding the signaling mechanisms in Cancer stem cells
• Mitochondrially targeted compounds novel therapeutic agents for Cancer novel therapeutic agents for Cancer
• Tumour Angiogenesis
Our goal is to understand the mechanism of tumor derived cytokines recruits and regulates the fate of infiltrating stem cells and how these cells affect tumor progression. We are focused in genetic and metabolic profiling that occur in tumor and MSCs.
The effects of micro-environmental stress on the regenerative activity of mesenchymal stem cells DST-UKIERI |
“Effects of 20-HETE in mediating VEGF and NO induced changes in tissues by distinct signaling mechanisms-DST. |
Centre of Excellence for Advanced Training and Research in Biomedical Applications -Tissue Engineering Osteoblasts and Human Dermal fibroblasts on PCL electrospun matrices sanctioned by MHRD. |
In vitro differentiation of mesenchymal stem cells into epithelial cell lineage - Clues from Gene profiling analysis-BUILDER PROGRAM. |
Delivered a Lecture on "Trends in Biotechnology- the Indian Scenario" in UK- India workshop on Industrial Biotechnology, organized by UK Science and Innovation Network and British Council,Chennai, 16th September,2016 |
Delivered a Lecture on "Curbing Cancer targeting the power house " in AMBICON organized by IMS and SUMS Hospital, Odisha (09-Jan-2016). |
Delivered a Lecture on "The Success story of Stem Cell Technology used for Pharmaceutical Technology " in Bio-Summit 2015 organized by Karpaga vinayaga college of Engineering & technology, Kanchipuram (08-Jan-2015). |
Delivered a Lecture on "Role of stem cells in the ageing endothelium" in ARCHA Symposium organized by Aston University, UK (16-Jul-2014). |
Delivered a Lecture on "Pitfalls in Regenerative Medicine-An Insight" in Future Trends in Biotechnology organized by PSG College of Technology, Coimbatore,India (03-May-2014). |
Delivered a Lecture on "Therapeutic application of bone marrow derived MScs cultured on bioscaffolds" in National Conference on current research perspective in Biotechnology, Healthcare & Environment organized by Dr. M.G.R. Educational and research Institute Univ, India (16-Apr-2013). |
Delivered a Lecture on "Biocompataibility studies of novel customizable polyamide scaffold for supporting osteoblast regeneration- Chances and challe" in Special Seminar in Department of Biophysics. organized by Medical college of Wisconsin, USA (12-Dec-2012). |
Delivered a Lecture on "Advances in Stem cell Research" in National seminar on Molecular Medicine organized by MepcoSchlenk, EngeeneringCollege,, Sivakasi,India (29-Aug-2012). |
Delivered a Lecture on "Whats in and out in Stem cell Technology" in National conference on Medicinal applications and advances. Organized by Aandal Alagar Engineenering College, Chennai (03-Jun-2012). |
Delivered a Lecture on "Advances in confocal Microscopy" in 23rd National congress of Parasitology organized by Indian society of Parasitology & Anna Univeristy, India (11-Nov-2011). |
Delivered a Lecture on "Recent trends in Bioscience- Advent & ambiguities" in Seminar organized by Dr. M.G.R. Educational and research institute Univ, India (29-Aug-2011). |
Delivered a Lecture on "Stem cells Boon or Bane" in Seminar on Biotechnology Uk and Indian Perspective organized by Centre for Biotechnology Anna University, India (11-Aug-2011). |
Delivered a Lecture on "Stem cell Technology" in Future perspectives in Biotechnology organized by Science City, Chennai., India (15-Dec-2010). |
Delivered a Lecture on "Novel Therapeutic approaches of Arachidonic acid derivatives" in Conducted Special Seminar on Department of Biochemistry organized by Sri Ramachandra Medical college and Research Insti, India (12-Jun-2009). |
Delivered a Lecture on "The RNA Avatars" in Seminar on Advanced Techniques in Biochemistry organized by Sri Ramachandra Medical college and Research Insti, India (10-May-2009). |
• Reviewer for Elsevier Publications
• Reviewer, PLOS journals
• Member of Animal Ethical Committee, Anna University
• Member of national screening committee for the selection of Fulbright-Nehru Post-Doctoral Grant applicants in the area of Science and Technology sponsored by USIEF
• Member of Japanese Biochemical Society
• Member of American Heart Association
• Expert Member, Institutional Committee for Stem Cell Research and Therapy (IC-SCRT,JIPMER, India
Number of Ph.D Scholars Guided | 5 |
Number of Ph.D Scholars Guiding | 5 |
Number of M.S (By Research) Scholars Guided | 4 |
Number of M.S (By Research) Scholars Guiding | 2 |
Number of M.E./ M.Tech. Projects Guided | 26 |
Number of M.E./ M.Tech. Projects Guiding | 5 |
Number of PostDoctoral Fellow | 3 |
All | Since 2014 | |
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Citations | 2095 | 2095 |
h-index | 24 | 21 |
i10-index | 35 | 29 |
BALARAMAN KALYANARAMAN, PhD Chairman and Professor of Biophysics Medical College of Wisconsin USA |
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ELIZABETH ROGERS JACOBS, MD Professor and Chief Pulmonary Medicine Medical College of Wisconsin USA |
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MICHAEL KRON, MD, MS Dept of Medicine Medical college of Wisconsin USA |
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Dr MEETHA MEDHORA Professor, Radiation Oncology, Medical College of Wisconsin USA |
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JOHN E. BAKER PhD Professor, Department of Surgery Division of Cardiothoracic Medical College of Wisconsin USA |
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RAJASINGH JOHNSON Division of Cardiovascular Diseases Kansas Medical Center Kansas USA |
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EUSTACE JOHNSON PhD Life and Health Sciences Aston University UK |
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ZELJKO J. BOSNJAK PhD Professor Department of Medicine Division of Endocrinology Medical College of Wisconsin USA |
Dr.C.D.Anuradha, Professor, Department of Biotechnology
Anna University, Chennai 600025
anu@annauniv.edu
anushivan@gmail.com
044-22358384